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WebNew farnesyl phosphonate derivatives of phenylalanine have been prepared as inhibitors of farnesyl-protein transferase (FPT). Enzyme inhibition studies with bovine brain FPT and rat liver squalene synthase show that compound Full-size image (<1 K) is a new, potent and selective FPT inhibitor. Web- L Phenylalanine Excipient - L Pyroglutamic Acid - L Rhamnose Excipient - L Serine Excipient - L Threonine Excipient - L-Alanine - L-Arginine - L-Aspartic Acid - L-Valine Excipient - Myristyl Alcohol - Octyldodecanol - Oleyl Alcohol - PEG-25 Hydrogenated Castor Oil - polyethylene glycol - Polysorbate 20 smith and nephew careers uk
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